Sequence Review: The Insurance Play (2026)

Here's the deal with Sequence: if your insurance covers GLP-1 medications, this is the platform to use. Full stop. Nothing else comes close on price for insured patients.

If your insurance doesn't cover GLP-1s, the self-pay pricing isn't compelling enough to choose Sequence over more established options. It's a one-trick pony — but it's a very good trick.

The Insurance Advantage

Most GLP-1 telehealth platforms are cash-pay only. Sequence actually runs your insurance benefits before you commit.

With qualifying insurance:

• Membership: $99-199/month
• Medication: Your copay (potentially $25-75/month for brand-name Wegovy or Zepbound)
• Total: as low as $124-274/month

Compare that to $300-500/month cash-pay elsewhere. For insured patients, Sequence could save $200-300/month. Over a year, that's $2,400-3,600. That's not a minor difference — that's a game-changer.

The catch: Not everyone qualifies. Coverage depends on your specific plan, BMI, state, and whether your insurer covers anti-obesity meds at all. Sequence is transparent about this during the benefits check, but disappointment is real.

Clinical Quality

The clinical quality is the highest we've encountered in telehealth weight loss. Sequence specifically recruits obesity medicine specialists — many with ABOM board certification. Not generalists moonlighting in weight loss.

Our initial video consultation: 30 minutes. Detailed follow-ups on metabolic history, evidence-based treatment protocol with monitoring milestones, specific lab markers to track. It felt like visiting a specialist's office, not clicking through a telehealth flow.

Follow-ups were equally impressive. Labs at 4 weeks, physician walked through results, dose escalation tied to actual data (tolerability, weight trajectory, lab markers). Check-in messages every 10-14 days — personalized, not templates.

The Full Pricing Picture

Without insurance (self-pay):

• Membership: $199/month
• Compounded semaglutide: $149-299/month
• Compounded tirzepatide: $249-399/month
• Total: $348-598/month

That's not competitive with Remedy Meds ($199-399 all-in). The self-pay path only makes sense if you really value the specialist-level clinical care.

Platform rough edges: No native app (mobile web only), scheduling through mix of in-app messaging and email (confusing), and they're not in all states yet. Founded 2022 — they're still building.

Who Sequence Is Best For

Best fit: patients with insurance that covers GLP-1 medications. Check your benefits first. If they cover Wegovy or Zepbound, Sequence is the most affordable path to treatment by a wide margin.

Also good for: People who want obesity-specialized physicians, complex metabolic profiles, and structured clinical protocols.

Skip it if: Your insurance doesn't cover GLP-1s (self-pay pricing isn't compelling), you want to start quickly (2-3 week onboarding), or polished app design matters to you.

For most cash-pay patients: Remedy Meds delivers faster onboarding, clearer pricing, and a smoother experience at a lower total cost.