Retatrutide Dosing Schedule (2026)
Simultaneously activates three receptors — GLP-1, GIP, and glucagon — producing stronger appetite suppression and metabolic effects than dual or single agonists. Average weight loss: 24% in clinical trials.
24%
Avg Weight Loss
Not yet available (pending FDA approval)
Compounded Price
Weekly
Injection Frequency
4
Dose Options
Retatrutide Dosing Schedule
Retatrutide is administered as a weekly subcutaneous injection. The dosing schedule follows a gradual titration to minimize side effects and find your optimal dose.
Available Doses
Retatrutide is available in the following doses: 1mg, 4mg, 8mg, 12mg.
Titration Schedule
Treatment starts at the lowest dose (1mg) and increases every 4 weeks based on tolerability. Your healthcare provider will guide the titration pace based on your response and any side effects you experience.
- Weeks 1-4: 1mg once weekly
- Weeks 5-8: 4mg once weekly
- Weeks 9-12: 8mg once weekly
- Weeks 13-16: 12mg once weekly
Your provider may adjust the pace of titration if you experience significant side effects. Never change your dose without consulting your healthcare provider.
Retatrutide FAQ
How much does Retatrutide cost?
Compounded Retatrutide costs Not yet available (pending FDA approval) through telehealth providers. Brand-name versions (Pending FDA approval) cost Not yet available (Phase 3 trials) without insurance.
How much weight can I lose on Retatrutide?
Clinical trials show an average weight loss of 24% of body weight on Retatrutide. Individual results vary based on dosage, diet, and exercise habits.
What are Retatrutide side effects?
Common side effects include nausea, diarrhea, decreased appetite, vomiting, constipation. Most side effects are temporary and resolve within 4-8 weeks as your body adjusts.
Is Retatrutide taken daily or weekly?
Retatrutide is administered as a weekly subcutaneous injection. It uses a pre-filled pen device for subcutaneous injection.
What doses is Retatrutide available in?
Retatrutide is available in 1mg, 4mg, 8mg, 12mg doses. Treatment starts at the lowest dose and increases every 4 weeks.