How Much Does Semaglutide Cost Without Insurance in 2026?

Let's get the headline number out of the way: without insurance, semaglutide costs between $149 and $1,349 per month depending on whether you go compounded or brand-name. That's a huge range, and the difference comes down to one decision.

The Price Range at a Glance

Option	Monthly Cost	Annual Cost
Brand-name Wegovy (cash pay)	$1,349	$16,188
Compounded (high-end provider)	$299-349	$3,588-4,188
Compounded (mid-range provider)	$199-299	$2,388-3,588
Compounded (budget provider)	$149-199	$1,788-2,388

Brand-Name (Wegovy) Without Insurance

Wegovy's list price is approximately $1,349.02 per month. That's Novo Nordisk's official pricing. Without insurance, that's what you're looking at.

Novo Nordisk does offer savings programs for eligible patients, but these are primarily designed for insured patients whose plans don't cover the drug well. Cash-pay patients typically don't qualify for meaningful discounts.

At $16,188/year, brand-name cash-pay semaglutide is a non-starter for most people. This is why the compounding market exploded.

Compounded Semaglutide Costs by Provider

Provider	Starting Dose	Maintenance Dose	Includes
Remedy Meds ⭐	$199/mo	$299/mo	Everything (no hidden fees)
Found	$149-199/mo	$249-299/mo	Varies by plan tier
Ro	$145/mo	$249-299/mo	Medication only (Body Program extra)
Hims	$199/mo	$299-349/mo	Medication + consult
Calibrate	$399+/mo	$500+/mo	Full program (12-mo commitment)

Best value overall: Remedy Meds at $199-299/month all-inclusive. Transparent pricing, no games.

Annual Cost Reality Check

GLP-1 treatment is typically long-term. Plan for at least 12 months. What that actually looks like:

Year 1 at Remedy Meds: ~$199-299/month × 12 = $2,388-3,588
Year 1 at Hims: ~$199-349/month × 12 = $2,388-4,188
Year 1 at Calibrate: ~$400-600/month × 12 = $4,800-7,200
Year 1 brand-name cash: ~$1,349/month × 12 = $16,188

The difference between compounded and brand-name is $12,000-14,000 per year. For the same active ingredient.

How to Minimize Your Cost

Check your insurance first. Even if you think it won't cover it, verify. Use Sequence for free benefits checking.
Use HSA/FSA funds. Most GLP-1 telehealth is HSA/FSA eligible. That's pre-tax dollars.
Choose a transparent provider. Hidden fees add up. Remedy Meds charges what they say they charge.
Don't overpay for brand premium. Hims charges more for the same compounded medication. You're paying for the app, not better medicine.
Consider your actual dose needs. Not everyone needs max dose. Discuss with your provider whether a lower maintenance dose is appropriate — it'll cost less monthly.

Full provider cost comparison: cheapest GLP-1 programs in 2026

Frequently Asked Questions

Is there a generic semaglutide?

No generic exists yet. Novo Nordisk holds patent protection. Compounded semaglutide uses the same molecule but isn't technically a 'generic' — it's a compounded version made by licensed pharmacies.

Can I use HSA/FSA for semaglutide?

Most compounded GLP-1 providers accept HSA/FSA payment or provide documentation for reimbursement. Remedy Meds is HSA/FSA eligible. Check with your specific plan.

Is Costco semaglutide cheaper?

Costco and other retail pharmacies fill brand-name prescriptions. Without insurance, Wegovy at retail is ~$1,349/month. Compounded through telehealth is significantly cheaper.