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dosing

Questions about dosing related to GLP-1 medications.

9 questions in this category

What is the Starting Dose of Semaglutide?

The starting dose is 0.25mg weekly for the first 4 weeks, then increased to 0.5mg. This low starting dose reduces side effects as your body adjusts.

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How Often Do You Increase Semaglutide Dose?

Doses increase every 4 weeks: 0.25mg → 0.5mg → 1mg → 1.7mg → 2.4mg. Some people stay at lower doses if they're tolerating it well and losing weight.

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What is the Maximum Dose of Semaglutide?

The FDA-approved maximum dose for weight loss (Wegovy) is 2.4mg weekly. For diabetes (Ozempic), the max is 2mg. Compounded semaglutide follows the same dosing schedule.

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Where Do You Inject Semaglutide?

Semaglutide is injected subcutaneously (under the skin) in the abdomen, thigh, or upper arm. Rotate injection sites each week to prevent tissue buildup.

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What Happens if You Miss a Semaglutide Dose?

If you miss a dose, take it as soon as you remember — but only if your next scheduled dose is more than 2 days away. If it's within 2 days, skip and resume your normal schedule. Never double up.

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How Should You Store Semaglutide?

Unopened pens should be refrigerated (36-46°F). Once in use, pens can be stored at room temperature (up to 77°F) for up to 28 days. Keep away from heat and light.

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Can You Travel with Semaglutide on an Airplane?

Yes. TSA allows insulin and similar injectables in carry-on bags without the 3.4oz liquid limit. Bring your prescription label. Keep pens in a cooling case for flights over 4 hours.

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Pen vs. Vial: Which Semaglutide Format is Better?

Pens (auto-injectors) are easier and come pre-filled. Vials require drawing the dose with a syringe, which is cheaper but requires more steps. Compounded semaglutide often comes as a vial.

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What is the Starting Dose of Tirzepatide?

Tirzepatide starts at 2.5mg weekly for 4 weeks, then 5mg. The dose escalates every 4 weeks: 2.5 → 5 → 7.5 → 10 → 12.5 → 15mg maximum.

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